J Korean Neurosurg Soc.  2002 Jul;32(1):29-34.

Development of Upgraded Cortical Impact Model(Part I: Mechanics)

Affiliations
  • 1Department of Neurosurgery, Chung-Ang University School of Medicine, Seoul, Korea.
  • 2Department of Mechanical Engineering, Korea advanced institute of science and technology(KAIST), Daejeon, Korea.

Abstract


OBJECTIVE
Head trauma model is important and essential to development of new therapeutic modality. We present a upgraded head trauma model for experimental animals.
METHODS
Using pneumatic cylinder, solenoid valve, linear variable differential transformer(LVDT) and load cell, we developed "Chung-Ang University Hospital Model 1.0(CAUH-1)" based on controlled cortical impact model.
RESULTS
Changing pressure, impact velocity could be controlled up to 4m/sec. Using solenoid valve, we could control dwell time precisely. Real time impact force could be measured with load cell.
CONCLUSION
Controlling dwell time, impact velocity, depth of deformation, this model would reproduce variable degrees of head injury. This model is so precise and versatile that it would be useful in diverse animal experimental researches.

Keyword

Upgraded cortical impact model; Impact velocity; Pneumatic cylinder

MeSH Terms

Animal Experimentation
Animals
Craniocerebral Trauma
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