J Korean Neurosurg Soc.  2002 Nov;32(5):458-462.

Development of Upgraded Cortical Impact Model (Part II: Functional outcome)

Affiliations
  • 1Department of Neurosurgery, Chung-Ang University School of Medicine, Seoul, Korea. nsseokmin@hotmail.com
  • 2Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology(KAIST), Daejeon, Korea.

Abstract


OBJECTIVE
With the technical support from department of mechanical engineering, Korea Advanced Institute of Science and Technology(KAIST), we began to develop a better head trauma model named "Chung-Ang University Hospital Model 1.0(CAUH-1)" in March 2001 and completed it August 2001. In addition, we conduct functional tests(postural reflex, balance beam test, rotarod test, and etc) to verify this model.
METHODS
Twelve four hours after moderate head injury(air tank pressure : 125psi, impact velocity: 1.34m/sec, depth of deformation : 2.5mm, dwell time : 84.5msec), we conducted various functional tests. Then, we compared the results with those of sham group.
RESULTS
Using this device, we revive neurobehavioral changes(decreased reflexes, hemiparesis, decreased vestibulo-motor function) occuring after human head trauma.
CONCLUSION
In our opinion, this is a very useful experimental head trauma model and will be helpful to many head trauma researchers.

Keyword

Functional tests; Chung-Ang University Hospital Model; KAIST

MeSH Terms

Craniocerebral Trauma
Head
Humans
Korea
Paresis
Reflex
Rotarod Performance Test
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