J Korean Neurosurg Soc.  1989 Dec;18(7-12):1098-1102.

Histiocytosis X with Involvement of Pituitary Stalk: Case Report

Affiliations
  • 1Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea.
  • 2Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea.
  • 3Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea.
  • 4Department of Diagnostic Radiology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

A case of histiocytosis X with the involvement of pituitary stalk in a 5 year old boy was described. He presented with diabetes insipidus and the endocrinological study showed growth hormone deficiency. On computerized tomography and magnetic resonance imaging, the pituitary stalk was abnormally thick. Overlooking of the skull lesion on plain X-ray film led to an erroneous diagnosis of germ cell tumor'. Gross total removal of the lesion and chemotherapy were performed. In the differential diagnosis of suprasellar masses, this disease entity should be included. The importance of histological diagnosis of the infundibular lesion in cases of central diabetes insipidus is also emphasized.

Keyword

Histiocytosis X; Pituitary stalk; Diabetes insipidus; Growth hormone deficiency

MeSH Terms

Child, Preschool
Diabetes Insipidus
Diabetes Insipidus, Neurogenic
Diagnosis
Diagnosis, Differential
Drug Therapy
Germ Cells
Growth Hormone
Histiocytosis*
Histiocytosis, Langerhans-Cell*
Humans
Magnetic Resonance Imaging
Male
Pituitary Gland*
Skull
X-Ray Film
Growth Hormone
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