J Korean Neurol Assoc.
2001 Mar;19(2):170-172.
Dysarthria after Donepezil
- Affiliations
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- 1Department of Neurology, Kyunggi Provincial Hospital For The Elderly.
Abstract
- We report a case of speech disturbance as an unrecognized adverse effect of the selective acetylcholinesterase inhibitor, donepezil. A 79-year-old woman presented with progressive memory disturbance that began 3 years ago. A brain MRI and neuropsychological test suggested that she had Alzheimer's disease. She showed transient dysarthria 14 days after the initiation of donepezil. Isolated speech disturbances were not observed. Clinicians should be alert to the possibility of dysarthria as an adverse effect of donepezil. (J Korean Neurol Assoc 19(2):170~172, 2001)
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