J Korean Med Assoc.  2008 Dec;51(12):1151-1157. 10.5124/jkma.2008.51.12.1151.

Immunoglobulins for Prophylaxis or Treatment of Infectious Diseases

• Kim KH

• KMID: 2185975
• DOI: http://doi.org/10.5124/jkma.2008.51.12.1151

Abstract

Administration of antibodies as a passive immunization is indicated for the replacement of deficiencies, prophylaxis or amelioration of infectious diseases for susceptible individuals and those at high risk for complications of infections. Antibodies can be administered either as human or animal plasma or serum, as pooled human immunoglobulin (IG) for intravenous or intramuscular use, as high-titer human IG from immunized or convalescing donors, or as monoclonal antibodies. Immunoglobulins are widely used for prevention of hepatitis A and measles and specific immunoglobulins are used for prevention of hepatitis B, tetanus, rabies, and varicella in susceptible people. A humanized murine monoclonal antibodies against respiratory syncytial virus have been licensed. This paper reviews the current use and recommendation of antibody products for the prevention and treatment of infectious diseases.

Keyword

Passive Immunization; Immunoglobulins; Infection; Prevention; Treatment

MeSH Terms

Animals
Antibodies
Antibodies, Monoclonal
Chickenpox
Communicable Diseases
Hepatitis A
Hepatitis B
Humans
Immunization, Passive
Immunoglobulins
Measles
Plasma
Rabies
Respiratory Syncytial Viruses
Tetanus
Tissue Donors
Antibodies
Antibodies, Monoclonal
Immunoglobulins

Reference

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