J Korean Neurol Assoc.  2010 Aug;28(3):206-208.

Guillain-Barre Syndrome After Peripheral Blood Stem Cell Transplantation

Affiliations
  • 1Department of Neurology, Ewha Womans University School of Medicine, Seoul, Korea. pkd1165@ewha.ac.kr
  • 2Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
  • 3Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.

Abstract

Neuromuscular complications after hematopoietic stem cell transplantation are rarely reported. We report one male patient with ophthalmoplegia, flaccid paralysis, and hyporeflexia after peripheral blood stem cell transplantation (PBSCT). A cerebrospinal fluid study showed albuminocytologic dissociation, and nerve conduction studies revealed demyelinating polyneuropathies. Intravenous immunoglobulin was tried following a diagnosis of Guillain-Barre syndrome (GBS). After 11 months he was able to walk alone with a walker. This is probably the first report of GBS related to PBSCT in Korea.

Keyword

Guillain-Barre syndrome; hematopoietic stem cell transplantation

MeSH Terms

Dissociative Disorders
Guillain-Barre Syndrome
Hematopoietic Stem Cell Transplantation
Humans
Immunoglobulins
Korea
Male
Neural Conduction
Ophthalmoplegia
Paralysis
Peripheral Blood Stem Cell Transplantation
Polyneuropathies
Reflex, Abnormal
Walkers
Immunoglobulins
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