J Korean Neurol Assoc.  2015 Aug;33(3):191-195. 10.17340/jkna.2015.3.10.

Fatal Rhino-Orbital-Cerebral Mucormycosis Complicated with Thrombosis and Rupture of Mycotic Aneurysm in Distal Internal Carotid Artery

Affiliations
  • 1Department of Neurology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. choyj@paik.ac.kr
  • 2Department of Dermatology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
  • 3Department of Pathology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.

Abstract

Mucormycosis is a rare opportunistic infection caused by fungi of the order Mucorales that typically occurs in patients with diabetes or immunocompromised state. Rhino-orbital-cerebral mucormycosis is the most common type, often has a life-threatening outcome. Mucormycosis has specific vascular tropism complicating mucorthrombosis or mycotic aneurysm. We report a diabetic patient presenting with ophthalmoplegia, orbital necrosis, and contralateral hemiparesis, who suddenly progressed to coma and died of subarachnoid hemorrhage due to the rupture of mycotic aneurysm in distal internal carotid artery.

Keyword

Rhino-orbital-cerebral mucormycosis; Distal internal carotid artery; Mycotic aneurysm

MeSH Terms

Aneurysm, Infected*
Carotid Artery, Internal*
Coma
Fungi
Humans
Mucorales
Mucormycosis*
Necrosis
Ophthalmoplegia
Opportunistic Infections
Orbit
Paresis
Rupture*
Subarachnoid Hemorrhage
Thrombosis*
Tropism
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