J Korean Assoc Maxillofac Plast Reconstr Surg.  1999 Aug;21(3):266-269.

Vascular effects of the inferior alveolar nerve injection of 2% lidocaine hci with 1:100,000 epinephrine

Affiliations
  • 1Department of Oral & Maxillofacial Surgery, College of Dentistry, Chosun University.
  • 2Department of Oral Pathology, College of Dentistry, Chosun University.
  • 3Oral Biology Research Institute, College of Dentistry, Chosun University.

Abstract

This article discusses the vascular change of dorsal surface of tongue following inferior alveolar nerve block of 2% lidocaine HCl with 1:100,000 epinephrine. Twenty-two rats were randomly allocated to three groups: control group; without mandibular nerve block, experimental group 1; 2% lidocaine HCl, experimental group 2; 2% lidocaine HCl plus 1:100,000 epinephrine. The assessments were performed at 1-, 5-, 30-, 60-, 120-minute after inferior alveolar nerve block. Vessel diameters using the micrometer were measured and compared. Results showed that the increase in vascular constriction in group 3 was greater than those in groups 1 and 2. In conclusion, local anesthesia combined with epinephrine assures safer anesthesia for hemostasis.

Keyword

Vascular change; Lidocaine; 1:100,000 epinephrine

MeSH Terms

Anesthesia
Anesthesia, Local
Animals
Constriction
Epinephrine*
Hemostasis
Lidocaine*
Mandibular Nerve*
Rats
Tongue
Epinephrine
Lidocaine
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