J Korean Androl Soc.
1991 Dec;9(2):87-90.
Histopathologic review of cryptorchid testis under age of 6 years old
- Affiliations
-
- 1Department of Urology, School of Medicine, Kyungpook National University, Taegu, Korea.
- 2Department of Pathology, School of Medicine, Kyungpook National University, Taegu, Korea.
Abstract
- The orchiopexy should be done before the histologic change had occured. We examined structural and ultrastructural change of cryptorchid testis with light & electron microscopy, testicular biopsy were collected at the time of orchiopexy from 18 patients during the period from Jan., 1989 to Jun., 1990. The most considerable findings were as follows: 1. The ages of 18 patients ranged from 14 months to 72 months. We divided the patients on the basis of age, as from 0 to 24 months in 3 cases(group A), from 25 to 36 months in 9 cases(group B) and from 37 to 72 months in 6 cases(group C). 2. Mean Tubular Diameter was average 40.6+/-4.8micrometer in group A, 37.0+/-7.7micrometer in group B and 36.7+/-6.6micrometer in group C. From the age of 25 months the Mean Tubular Diameter showed decreasing pattern with the comparison by the Mengel's Mean Tubular Diameter of normal descended testis as normal control group. 3. We classified Mean Tubular Fertility Index(M.T.F.I.) as 3 criteria, minimal(above 50%), marked(30-50%) and severe(under 30%). There were 2 minimal and 1 marked in group A, 5 minimal, 3 marked and 1 severe in group B and 1 marked and 5 severe in group C. 4. By electron microscopy, from the age of 14 months, there were increased cellularity, vacuolization and dilated endoplasmic reticulum of spermatogenic and Sertoli cells. These findings offer further information about the optimal time for surgical treatment of cryptorchism, which in our opinion should be done when the patient is less than 2 years old.
