J Korean Acad Rehabil Med.  2002 Jun;26(3):358-362.

Treatment with Botulinum Toxin A in Continuous Facial and Neck Myokymia: A case report

Affiliations
  • 1Department of Rehabilitation Medicine, Seoul Veterans Hospital, Korea.
  • 2Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Korea.

Abstract

Myokymia is a clinical phenomenon characterized by undulating, vermicular, rippling and wavelike movements spreading across the muscle surface. Facial myokymia is an unusual complication of brainstem hemorrhage. It tends to occur in brainstem tumor or multiple sclerosis. We report a 51-year-old man with continuous facial and neck myokymia after brainstem hemorrhage, who revealed focal myokymic discharges in face, neck and pharyngolaryngeal muscles in-nervated by cranial nerve V, VII, X, and XI. After injection of 20-80 units of Botulinum toxin type A (Dysport ) to the left orbicularis oris, mentalis, mylohyoid and posterior belly of digastric muscles, amplitude of continuous myokymic discharges was markedly reduced. We recommend Botulinum toxin injection as a very effective therapeutic method in managing focal movement disorders.

Keyword

Myokymia; Brainstem; Botulinum toxin

MeSH Terms

Botulinum Toxins*
Botulinum Toxins, Type A
Brain Stem
Brain Stem Neoplasms
Facial Nerve Diseases
Hemorrhage
Humans
Middle Aged
Movement Disorders
Multiple Sclerosis
Muscles
Myokymia*
Neck*
Trigeminal Nerve
Botulinum Toxins
Botulinum Toxins, Type A
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