J Korean Child Neurol Soc.  1999 May;6(2):332-339.

Brain Magnetic Resonance Imaging Findings in Children with Cerebral Palsy: Compared between Preterm and Term Groups

• Yoo CH
• Yoon DY
• Cho HS
• Min KS
• Kim JW
• Ryoo KY

Abstract

PURPOSE: We used MRI to retrospectively analyze the brain of patients suffering from cerebral palsy. Our aim is to determine MRI's role in the assessment of brain damage, the relationship of gestational age.
METHODS
A total of 66 patients (29 preterm group and 37 term group), who visited Kang-Dong Sacred Heart Hospital from January, 1994 to July, 1998, were enrolled in this study.
RESULTS
Among the 29 in the preterm group, 13 patients showed MR images of hypoxic ischemic injury in which periventricular leukomalacia (PVL) and multifocal ischemic necrosis in 12 (41.3%) and 1 (3.4%) respectively. Neuronal migration disorders were 6 (20.8%), other congenital malformations 5 (17%) and normal MR images 5 (17%) in this preterm group. Among the 37 in the term group, 22 patients showed MR images of hypoxic ischemic injury in which selective neuronal necrosis were 11 (29.7%), PVL 4 (10.8%), focal and multifocal ischemic necrosis 4 (10.8%) and status marmoratus 3 (8.1%). Neuronal migration disorders were 4 (10.8%), other congenital malformations 5 (13.5%) and normal MR images 6 (16.2%) in the term group.
CONCLUSION
MRI provided useful information in a majority of children with cerebral palsy. Hypoxic ischemic injury was significantly different in preterm and term groups. PVL was frequent in the preterm group and selective neuronal necrosis was statistically common in the term group.

Keyword

Cerebral palsy; MRI findings

MeSH Terms

Brain*
Cerebral Palsy*
Child*
Gestational Age
Heart
Humans
Infant, Newborn
Leukomalacia, Periventricular
Magnetic Resonance Imaging*
Movement Disorders
Necrosis
Neuronal Migration Disorders
Neurons
Retrospective Studies