J Adv Prosthodont.  2009 Mar;1(1):10-18. 10.4047/jap.2009.1.1.10.

Histomorphometry and stability analysis of early loaded implants with two different surface conditions in beagle dogs

• Kim DS
• Kim DG
• Park CJ
• Cho LR

• KMID: 2176333
• DOI: http://doi.org/10.4047/jap.2009.1.1.10

Abstract

STATEMENT OF PROBLEM: Despite an improved bone reactions of Mg-incorporated implants in the animals, little yet has been carried out by the experimental investigations in functional loading conditions. PURPOSE: This study investigated the clinical and histologic parameters of osseointegrated Mg-incorporated implants in early loading conditions. MATERIAL AND METHODS: A total of 36 solid screw implants (diameter 3.75 mm, length 10 mm) were placed in the mandibles of 6 beagle dogs. Test groups included 18 Mg-incorporated implants. Turned titanium implants served as control. Gold crowns were inserted 4 weeks after implant placement and the dogs were immediately put on a food diet. Implants were observed for 10 weeks after loading. Radiographic assessments and stability tests were performed at the time of fixture installation, 2nd stage surgery, 4 weeks after loading, and 10 weeks after loading. Histological observations and morphometrical measurements were also performed. RESULTS: Of 36 implants, 33 displayed no discernible mobility, corresponding to successful clinical function. There was no statistically significant difference between test implants and controls in marginal bone levels (P = .46) and RFA values. The mean BIC% in the Mg-implants was 54.5 +/- 8.4%. The mean BIC% in the turned implant was 45.3 +/- 12.2%. These differences between the Mg-implant and control implant were statistically significant (P = .005). CONCLUSIONS: The anodized, Mg-incorporated implant demonstrated significantly more bone-to-implant contact (BIC) in early loading conditions. CLINICAL IMPLICATIONS: The results of this study in beagle dogs suggest the possibility of achieving predictable stability of early loaded free-standing dental implants with Mg-incorporated surface.

Keyword

Oxidized implant; Histomorphometry; Early loading

MeSH Terms

Animals
Crowns
Dental Implants
Diet
Dogs
Mandible
Titanium
Dental Implants
Titanium

Figure

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  Fig. 1 Control turned implant (a) and test Mg-implant (b).

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  Fig. 2 XPS survey spectra (a) and SEM micrograph of Mg-implant surface (b).

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  Fig. 3 Delivery of crowns; Crowns in the model (a) and in the mouth (b).

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  Fig. 4 customized XCP device (a) and periapical radiograph (b).

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  Fig. 5 Bone area within the threads (R1, R2) and their mirror image areas (S1, S2).

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  Fig. 6 Marginal bone level change.

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  Fig. 7 ISQ value change.

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  Fig. 8 Bone-implant contact area.

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