J Breast Cancer.  2011 Dec;14(4):333-336. 10.4048/jbc.2011.14.4.333.

A Rare Case of Male Primary Breast Lymphoma

Affiliations
  • 1Department of Radiodiagnosis, Government Medical College and Hospital, Nagpur, India. drjawahar_12@rediffmail.com

Abstract

Primary lymphoma of the breast is a rare occurrence because of the paucity of lymphoid tissue in the breast and is an even rarer entity in the male breast. Imaging, along with tissue diagnosis goes a long way in diagnosing breast lymphoma which has a significantly different management scheme than other breast neoplasms with respect to radio-chemotherapy rather than surgical resection. We present a case of primary male breast lymphoma which was evaluated with magnetic resonance imaging as well as other conventional imaging modalities and was treated by chemotherapy with a 7-month follow-up.

Keyword

Breast; Lymphoma; Male; Perfusion magnetic resonance imaging

MeSH Terms

Breast
Breast Neoplasms
Follow-Up Studies
Humans
Lymphoid Tissue
Lymphoma
Magnetic Resonance Angiography
Magnetic Resonance Imaging
Male

Figure

  • Figure 1 High frequency ultrasound using 12 to 3 MHz broadband linear array transducer revealed a well-defined lobulated relatively homogenous, hypoechoic mass.

  • Figure 2 On color Doppler, the lesion showed mild vascularity.

  • Figure 3 T1-weighted MR image showing a well-defined isointense, lobulated lesion and maintained fat planes with the underlying pectoralis muscle.

  • Figure 4 T2-weighted MR image showing a mildly hyperintense lesion compared to muscle.

  • Figure 5 Dynamic MR imaging showing a Type II perfusion curve.

  • Figure 6 H&E stained image showing diffuse large B cell lymphoma (H&E, ×100).

  • Figure 7 Immunohistochemical study showing diffuse positivity of diffuse round cells for CD 20 (Immunohistochemical stain, ×600).


Cited by  1 articles

Diffuse Large B-Cell Lymphoma with Involvement of the Breast and Testis in a Male Patient
Eunji Choi, Jae-Cheol Jo, Dok Hyun Yoon, Shin Kim, Kyoungmin Lee, Jooryung Huh, Chan-Sik Park, Sang Wook Lee, Cheolwon Suh
Cancer Res Treat. 2015;47(3):539-543.    doi: 10.4143/crt.2013.245.


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