J Gynecol Oncol.  2008 Dec;19(4):270-274. 10.3802/jgo.2008.19.4.270.

A case of huge sclerosing stromal tumor of the ovary weighing 10 kg in a 71-year-old postmenopausal woman

Affiliations
  • 1Department of Obstetrics and Gynecology, Wonju College of Medicine, Yonsei University, Wonju, Korea. visionhk@yonsei.ac.kr
  • 2Department of Pathology, Wonju College of Medicine, Yonsei University, Wonju, Korea.

Abstract

Sclerosing stromal tumor (SST) is a rare benign neoplasm of ovarian stromal origin and predominantly affects young women in the second and third decades. This tumor characteristically differentiates itself histologically and clinically from both thecomas and fibromas. We present a case of huge SST of the ovary weighing 10 kg in a 71-year-old postmenopausal woman with a brief review of the literature.

Keyword

Sclerosing stromal tumor; Ovary

MeSH Terms

Aged
Female
Fibroma
Humans
Ovary
Thecoma

Figure

  • Fig. 1 Contrast-enhanced CT scans show a 43.9×28.3×34.7 cm cystic mass with peripheral enhancement. (A) Axial image. (B) Coronal image.

  • Fig. 2 Gross finding of left ovarian mass (45×33×27 cm). (A) The external surface is relatively smooth but shows diffuse hyperemic appearance with focal yellow discoloration. (B) On opening, it is a multilocular cystic mass with solid portion, showing diffuse necrotic and hemorrhagic, variegated appearance. The content varies from blood clots, dark brown serous fluid, yellow mucinous fluid, and to dark brown necrotic tissue.

  • Fig. 3 Microscopic finding of viable area. (A) It shows an alternative pseudolobular pattern which consist of cellular and hypocellular areas (H&E, ×40). (B) The former consists of oval to round vaculated lutenized thecalike cells and fibroblasts. The latter consists of dense collagenous tissue (H&E, ×400). Immunohistochemistry shows positive for Desmin (C) and smooth muscle actin (D) (×400).


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