Int Neurourol J.  2012 Dec;16(4):205-208.

Atypical Epidermoid Cyst in Renal Pelvis and Histogenetic Implications

Affiliations
  • 1Department of Pathology, Dankook University College of Medicine, Cheonan, Korea.
  • 2Department of Urology, Dankook University College of Medicine, Cheonan, Korea. multiorigins@yahoo.com

Abstract

Since the renal epidermoid cyst is too rare, the mechanisms of squamous morphogenesis have not well characterized. A 73-year-old female was referred with an incidentally detected renal pelvis mass. Abdominopelvic computed tomography scan revealed a noncalcified soft tissue mass in the renal pelvis. Total nephroureterectomy was performed under the impression of a renal pelvis malignancy. The patient was discharged without postoperative complication. The outer surface of mass lesion was lined with urothelia and squamous epithelia, containing keratinous materials. The urothelia were positively stained against uroplakin II and cytokeratin 7, whereas almost of the squamous epithelia were negative with uroplakin II. The two different epithelia were generally sharply demarcated. Interestingly, some part of squamous epithelia contained uroplakin-positive and many more cytokeratin 7-positive cells. The atypical clinical features in our case can reconsider the diagnostic clues of renal epidermoid cysts that have been reported before, and the unique immunohistochemical results may understand the histogenetic implications of the lesion.

Keyword

Epidermal cyst; Uroplakins; Pathology; Kidney

MeSH Terms

Epidermal Cyst
Female
Humans
Keratin-7
Keratins
Kidney
Kidney Pelvis
Morphogenesis
Postoperative Complications
Uroplakin II
Uroplakins
Keratin-7
Keratins
Uroplakin II
Uroplakins
Full Text Links
  • INJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr