Blood Res.  2013 Dec;48(4):296-297. 10.5045/br.2013.48.4.296.

Primary diffuse large B-cell lymphoma of the bone marrow in a frail and elderly patient successfully treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone

• Niscola P
• Palombi M
• Fratoni S
• Perrotti A
• de Fabritiis P

• KMID: 2172880
• DOI: http://doi.org/10.5045/br.2013.48.4.296

Abstract

No abstract available.

MeSH Terms

Aged*
B-Lymphocytes*
Bone Marrow*
Cyclophosphamide*
Doxorubicin*
Humans
Lymphoma, B-Cell*
Prednisone*
Vincristine*
Rituximab
Cyclophosphamide
Doxorubicin
Prednisone
Vincristine

Figure

• 

  Fig. 1 (A) Bone marrow biopsy (Giemsa stain, high magnification) showing a neoplastic infiltrate composed predominantly of blastic cells with centroblastic morphology, with minor components composed of small centrocyte-like cells. These findings are indicative of diffuse large B-cell lymphoma with features suggestive of a centrofollicular origin. (B) Immunostaining with CD20L26 antibodies reveals diffuse membrane expression in neoplastic cells. (C) Immunostaining with BCL2 reveals diffuse cytoplasmatic expression by neoplastic cells.

Reference

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