Ann Dermatol.  2004 Jun;16(2):71-75. 10.5021/ad.2004.16.2.71.

A Case of Idiopathic Lymphocytoma Cutis

• Kim JE
• Kim MY
• Park YM
• Kim HO

• KMID: 2172115
• DOI: http://doi.org/10.5021/ad.2004.16.2.71

Abstract

The pseudolymphoma of the skin has the architectural and cytological features of a neoplastic proliferation of lymphoid tissue but pursue a benign course. Cutaneous B cell pseudolymphoma (CBPL) shares many histopathologic and clinical features with cutaneous B cell lymphoma (CBCL). Therefore, the differentiation between CBPL and CBCL is often very difficult, but it is important because each of them has a different therapeutic consequence. Recently, immunoglobulin gene rearrangement is considered as a reliable technique for differentiation of CBPL with CBCL. We herein report a case of idiopathic lymphocytoma cuffs, showing a typical nodular infiltrate of lymphocytes that formed a follicular germinal center resembling reactive lymph nodes with numerous tingible bodies, and that revealed a polyclonality in the immunoglobulin gene rearrangement.

Keyword

Cutaneous B cell pseudolymphoma; Idiopathic lymphocytoma cutis; Immunoglobulin gene rearragnement

MeSH Terms

Genes, Immunoglobulin
Germinal Center
Lymph Nodes
Lymphocytes
Lymphoid Tissue
Lymphoma, B-Cell
Pseudolymphoma*
Skin