Ann Dermatol.  2004 Jun;16(2):67-70. 10.5021/ad.2004.16.2.67.

Two Cases of Cutaneous Cytomegalovirus Infection in Immunocompromised Patients

• Park JH
• Oh JJ
• Lee ES

• KMID: 2172114
• DOI: http://doi.org/10.5021/ad.2004.16.2.67

Abstract

Cytomegalovirus (CMV) is a major cause of morbidity and mortality in immunocompromised patients. CMV can cause pneumonia, retinitis, gastrointestinal ulcers, and widely disseminated disease, but cutaneous CMV is rare. We report two cases of cutaneous CMV infection presenting as perianal ulcers. A 54 year-old male who had liver transplantation and a 72-year-old male, who was treated with chemotherapy for angioimmunoblastic T-cell lymphoma, presented with perianal ulcers and had systemic symptoms of CMV infection with CMV antigenemia. They had multiple ulcerations with erythematous bases on the perianal area, and histopathologic examinations showed large atypical cytomegalic cells in the dermis, and immunohistochemical stains, with the anti-CMV antibody showed positive reactions.

Keyword

Cytomegalovirus; Perianal ulcer

MeSH Terms

Aged
Coloring Agents
Cytomegalovirus Infections*
Cytomegalovirus*
Dermis
Drug Therapy
Humans
Immunocompromised Host*
Liver Transplantation
Lymphoma, T-Cell
Male
Mortality
Pneumonia
Retinitis
Ulcer
Coloring Agents