Ann Dermatol.  2009 Feb;21(1):95-97. 10.5021/ad.2009.21.1.95.

A Patient with Delayed Contact Dermatitis to Coral and She Displayed Superficial Granuloma

• Ahn HS
• Yoon SY
• Park HJ
• Lee JY
• Cho BK

• KMID: 2172079
• DOI: http://doi.org/10.5021/ad.2009.21.1.95

Abstract

Contact with coral may cause a rare type of contact dermatitis, and the resulting skin reaction can be divided into different reactions: the acute, delayed and chronic types of coelenterate dermatitis. Granulomas of delayed skin reactions have rarely been reported. Herein, we report on a rare case of a delayed reaction of the skin to coral injury, and the patient displayed superficial granulomas and atypical CD30+ lymphocytes.

Keyword

Contact dermatitis; Coral; Granuloma

MeSH Terms

Anthozoa
Dermatitis
Dermatitis, Contact
Granuloma
Humans
Lymphocytes
Skin

Figure

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  Fig. 1 An erythematous patch, 2.5 cm in diameter, was composed of multiple flat papules on the left knee.

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  Fig. 2 (A) Dense, superficial perivascular and periadnexal infiltrates of lymphocytes and eosinophils in the dermis and focal, superficial, small epithelioid granulomas with multinucleated giant cells (H&E, ×100). (B, C) Superficial patchy CD30+ nucleolated lymphocytes in the inflammatory infiltrates and the magnified view (alkaline phosphatase-antialkaline phosphatase, ×100, ×400).

Reference

1. Tong D. Coral dermatitis in the aquarium industry. Contact Dermatitis. 1995. 33:207–208.

2. Miracco C, Lalinga AV, Sbano P, Rubegni P, Romano C. Delayed skin reaction to Red Sea coral injury showing superficial granulomas and atypical CD30+ lymphocytes: report of a case. Br J Dermatol. 2001. 145:849–851.

3. Weedon D, Strutton G. Weedon D, Strutton G, editors. Marine injuries. Skin pathology. 1997. 1st ed. Edinburgh: Churchill Livingstone;611–619.

4. Addy JH. Red sea coral contact dermatitis. Int J Dermatol. 1991. 30:271–273.

5. Camarasa JG, Nogues Antich E, Serra-Baldrich E. Red Sea coral contact dermatitis. Contact Dermatitis. 1993. 29:285–286.

6. David EE, Rosalie E, Bernett LJ Jr, Gerorge FM. Lever's histopathology of the skin. 2005. 9th ed. Philadelphia: Lippincott Williams & Wilkins;384–386.

7. Lucey DR, Clerici M, Shearer GM. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin Microbiol Rev. 1996. 9:532–562.

8. Dummer W, Rose C, Brocker EB. Expression of CD30 on T helper cells in the inflammatory infiltrate of acute atopic dermatitis but not of allergic contact dermatitis. Arch Dermatol Res. 1998. 290:598–602.