Ann Dermatol.  2011 Feb;23(1):111-114. 10.5021/ad.2011.23.1.111.

Branch-shaped Cutaneous Hypopigmentation and Atrophy after Intralesional Triamcinolone Injection

• Jang WS
• Park J
• Yoo KH
• Han TY
• Li K
• Seo SJ
• Hong CK

• KMID: 2171968
• DOI: http://doi.org/10.5021/ad.2011.23.1.111

Abstract

Cutaneous changes after local corticosteroid administration may include dermal atrophy, hyperpigmentation, alopecia, and hypopigmentation. Linear hypopigmentation and atrophy after intralesional injection of triamcinolone acetonide has been reported in the literature as a very rare side effect. A 30-year-old woman visited our dermatology department for a linear hypopigmented patch with atrophy from her left foot to the lower margin of the knee. The lesion developed after injection of an intralesional corticosteroid. The patient was diagnosed with linear hypopigmentation and atrophy secondary to the triamcinolone injection.

Keyword

Atrophy; Hypopigmentation; Triamcinolone

MeSH Terms

Adult
Alopecia
Atrophy
Dermatology
Female
Foot
Humans
Hyperpigmentation
Hypopigmentation
Injections, Intralesional
Knee
Triamcinolone
Triamcinolone Acetonide
Triamcinolone
Triamcinolone Acetonide

Figure

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  Fig. 1 (A) Hypopigmented patch with atrophy on the patient's left foot. (B) Linear hypopigmentation and atrophy along the left dorsal foot up to the lower margin of the knee.

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  Fig. 2 (A) The lesional side shows epidermal atrophy and flattening rete ridges (H&E, ×200). (B) The lesional side shows hypopigmentation of the basal layer (Fontana-Masson, ×200). (C) The normal side shows non-specific change (H&E, ×200). (D) In the normal side, pigmentation of the basal layer is not decreased (Fontana-Masson, ×200).

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