Ann Dermatol.  2015 Oct;27(5):614-615. 10.5021/ad.2015.27.5.614.

Successful Treatment of Livedoid Vasculitis with Primary Antiphospholipid Syndrome by Using Aspirin and Low Dose Warfarin Combination Therapy

• So BJ
• Park JB
• Yoo MG
• Kim IH
• Son SW

• KMID: 2171465
• DOI: http://doi.org/10.5021/ad.2015.27.5.614

Abstract

No abstract available.

MeSH Terms

Antiphospholipid Syndrome*
Aspirin*
Vasculitis*
Warfarin*
Aspirin
Warfarin

Figure

• 

  Fig. 1 (A) Lesions showing purpura and irregular ulcerations at first visit. (B) Lesions showing almost complete clinical remission at 2 months after treatment.

• 

  Fig. 2 (A) Dilated capillaries in the upper dermis (H&E, ×40). (B) Vessel walls are thickened and contain fibrinoid material (H&E, ×100).

Reference

1. Kim JE, Park SY, Sinn DI, Kim SM, Hong YH, Park KS, et al. Ischemic neuropathy associated with livedoid vasculitis. J Clin Neurol. 2011; 7:233–236.

2. Grasland A, Crickx B, Blanc M, Pouchot J, Vinceneux P. Livedoid vasculopathy (white atrophy) associated with anticardiolipin antibodies. Ann Med Interne (Paris). 2000; 151:408–410.

3. Kim JE, Park HJ, Lee JY, Cho BK. A case of leg ulcer with SLE and antiphospholipid syndrome. Korean J Dermatol. 2006; 44:738–740.

4. Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006; 4:295–306.

5. Acland KM, Darvay A, Wakelin SH, Russell-Jones R. Livedoid vasculitis: a manifestation of the antiphospholipid syndrome. Br J Dermatol. 1999; 140:131–135.