Ann Dermatol.  2016 Apr;28(2):275-277. 10.5021/ad.2016.28.2.275.

Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type Involving Skin Masquerading as Eczema

• Kim JS
• Choi M
• Nam CH
• Kim MH

• KMID: 2171399
• DOI: http://doi.org/10.5021/ad.2016.28.2.275

Abstract

No abstract available.

MeSH Terms

Eczema*
Lymphoma*
Skin*

Figure

• 

  Fig. 1 Erythematous papules and plaques with areas of brownish hyperpigmentation on (A), (B) right upper back and (C) left thigh.

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  Fig. 2 (A) Mixed atypical lymphoid cells and histiocytic cells along superficial and deep perivascular area (H&E, ×40). (B) Lymphocytic infiltration in perivascular pattern, with pale cytoplasm and dense chromatin with irregularly shaped nuclei (H&E, ×400). (C) Immunohistochemical study showing CD4 positivity in majority of lymphoid cells (CD4, ×40). (D) Immunohistochemical study showing CD56 positivity in interstitial, periadnexal lymphoid cells (CD56, ×40). (E) Immunohistochemical study showing strong and profuse positivity in in situ hybridization for Epstein-Barr virus (EBV). Some of the EBV positive cells are invading vessel wall (red-arrows) (EBV in situ, ×400).

Reference

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