Ewha Med J.  2014 Dec;37(Suppl):S5-S9. 10.12771/emj.2014.37.S.S5.

Chemotherapy in Small Cell Lung Cancer with End-Stage Renal Disease on Hemodialysis

Affiliations
  • 1Department of Internal Medicine, National Cancer Center, Goyang, Korea. kiwonkim@ncc.re.kr

Abstract

Small cell lung cancer is primarily treated with chemotherapy. For patients with end-stage renal disease (ESRD), systemic chemotherapy is often challenging since renal excretion of chemotherapeutic agents might be decreased due to impaired renal function, leading to increased toxicity. No consensus is made so far regarding appropriate dosage and combination of chemotherapeutic agents for patients on hemodialysis. We report two cases of chemotherapy without significant toxicity in small cell lung cancer patients who were on hemodialysis for ESRD.

Keyword

Small cell lung carcinoma; Drug therapy; Kidney failure, chronic; Renal dialysis

MeSH Terms

Consensus
Drug Therapy*
Humans
Kidney Failure, Chronic*
Renal Dialysis*
Small Cell Lung Carcinoma*
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