Korean J Dermatol.
1988 Dec;26(6):785-790.
A Studyof Dermal Mast Cells Number in End Stage of Renal Failure
Abstract
- We studied the relationship between dermal mast cell proliferation and pruritus in patients with end stage of renal failure. Skin biopsies were taken from 21 patients undergoing hemodialysis in end stage of renal failure. As a control, 12 pruritic patients without any internai problem were u.d. During the hemodialysis, 13 patient ha<) pruritus. Serum PTH levels were measured by radioimmunoassay. We have thought that the cause of pruritus in patients undergoing hemodialysis is related with dermal mast cell proliferation and a release of histamine. The results were as follows .' 1. Significantly larger numbers of dermal mast cells were found in hemodialysis patients than in the control (p<0.001). 2. Significantly larger mumbers of dermal mast cells were found in prnritic patients than in the non pruritic patients among hemodialysis patients (p<0.01). 3. There was no clear relationship between dermal mast cell proliferation and duration of hemodialysis or seum level of parathyroid hormone.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- End-stage renal failure in 124 children: analysis of etiology, age and interal from early renal failure to the end stage
- Dermal mast cell responses in Paragonimus westermani-infected mice
- Study of Relationship between Histologic Findings and Variation of Number of Mast cell in Psoriasis
- A Case of Segmental Morphea with Marked Mast Cell Infiltration
- Histochemical Study of Incipient Psoriasis: The Changes of Acid Mucopolysaccharide and Mast Cells of the Dermis in Initial Lesions of Psoriasis
