beta-glucuronidase Activity in Rheumatoid Arthritis and Osteoarthritis

Ko, Sang Hun

Abstract

OBJECTIVES
In ostroarthritis and rheumatoid arthritis, beta-glucuronidase activity was measured in body fluid to diagnose this special disease entities.
METHODS
The beta-glucuronidase activity was studied in the urine, serum and joint fluid. The level of this specimens were estimated by statistical sections.
RESULTS
1) The beta-glucuronidase activity in urine, serum and joint fluid of osteoarthritis patients were 0.09U/l urine, 0.14U/l serum, 0.06U/l joint fluid. The highest level of activity was in the serum. 2) The beta-glucuronidase activity on rheumatoid arthritis was 0.19U/l urine, 0.17U/l serum, 0.07U/l joint fluid. The highest increased level of activity was in the urine. 3) In the joint fluid and serum, there is the no mean of stistical analysis. But in the urine, there is marked meaning of statistical analysis(Male : p=0.0041, Female : p=0.0001).
CONCLUSION
beta-glucuronidase activity was influenced by osteoarthritis and rheumatoid arthritis. Especially in the urine, beta-glucuronidase activity was outstanding statistical meaning. According to disease entities, The level of activity was different from each specimen.