Ewha Med J.  1997 Mar;20(1):111-117. 10.12771/emj.1997.20.1.111.

Expression of Constitutive Nitric Oxide Synthase by Gastrointestinal Epithelial Cells

Affiliations
  • 1Department of Anatomy, Division of Neuroscience, College of Medicine, Ewha Medical Research Center, Ewha Womans University, Korea.

Abstract

The present study investgated if constitutive nitric oxide synthase(cNOS), especially neuronal type, is expressed in gastrointestinal epithelial cells of rat. Expression of cNOS was immunohistochemically determined. Some gastric epithelial cells were found to express cNOS. Although less than that by the gastric epithelial cells, cNOS was also found to be expressed by the intestinal epithelial cells. Thus it is possible that constitutive type of nitric oxide synbthase in gastrointestinal epithelial cells may play a role in normal gastrointestinal function.

Keyword

Gastrointestinal epithelium; Constitutive nitric oxide synthase

MeSH Terms

Animals
Epithelial Cells*
Neurons
Nitric Oxide
Nitric Oxide Synthase*
Rats
Nitric Oxide
Nitric Oxide Synthase
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