Ewha Med J.
1982 Dec;5(4):249-254. 10.12771/emj.1982.5.4.249.
Cerebrospinal Fluid Lactate Level Following Experimental Spinal Cord Injury
- Affiliations
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- 1Department of Neurosurgery, College of Medicine, Ewha Womans University, Korea.
- KMID: 2170732
- DOI: http://doi.org/10.12771/emj.1982.5.4.249
Abstract
- For the purpose of ascertaining the role and magnitude of ischemia of the spin-al cord following trauma the authors determine the lactate concentrations in cere-brospinal fluid(CSF). Laminectomies were performed at L2 under general anes-thesia with aseptic techniques. Paraplegia was produced by 400 gm-cm impact injury with impounder. Significant increases in CSF lactate levels occurring at Day 5. The prolonged elevation of CSF lactate indicates that tissue hypoxia plays a role in spinal cord damage and that there is a continuing hypoxia of metabolically active spinal cord tissue for several days post injury.
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