Infect Chemother.  2011 Feb;43(1):26-35. 10.3947/ic.2011.43.1.26.

Recent Advances in the Use of Anthelmintics for Treating Nematode Infections

• Chai JY

• KMID: 2170330
• DOI: http://doi.org/10.3947/ic.2011.43.1.26

Abstract

The recent trends of parasitic infections in Korea include remarkable decreases of soil-transmitted nematode infections and elimination of lymphatic filariasis. In comparison, enterobiasis (pinworm infection) continues to be prevalent among children and the cases of zoonotic tissue-invading nematode infection are slightly increasing or they are being increasingly diagnosed. In addition, imported parasitoses continue to be problems from the clinical and public health points of view. In this review, the advances in the management and anthelmintic treatment of these nematode infections are briefly reviewed. Albendazole, mebendazole, thiabendazole, flubendazole, pyrantel pamoate, pyrvinium pamoate, oxantel pamoate, levamisole, ivermectin, and diethylcarbamazine are the examples of anti-nematode anthelmintics that are currently being used. Although several of these drugs are known to be broad-spectrum anthelmintics, selection of each drug should be done specifically for each nematode infection, and with consideration of the specific conditions of each patient and the purposes, for example, when performing individual or mass treatment. It is hoped that the chemotherapy regimens reviewed here will help physicians to treat their patients infected with nematode parasites.

Keyword

Anthelmintics; Nematode; Albendazole; Mebendazole; Ivermectin; Diethycarbamazine

MeSH Terms

Albendazole
Anthelmintics
Child
Diethylcarbamazine
Elephantiasis, Filarial
Enterobiasis
Humans
Ivermectin
Korea
Levamisole
Mebendazole
Nematode Infections
Parasites
Public Health
Pyrantel Pamoate
Pyrvinium Compounds
Thiabendazole
Albendazole
Anthelmintics
Diethylcarbamazine
Ivermectin
Levamisole
Mebendazole
Pyrantel Pamoate
Pyrvinium Compounds
Thiabendazole