Cancer Res Treat.  2012 Mar;44(1):63-68.

Five Cases Report of Solid Tumor Synchronously with Hematologic Malignancy

• Cui Y
• Liu T
• Zhou Y
• Ji Y
• Hou Y
• Jin W
• Feng Y

Abstract

The reported incidence of synchronous multiple primary cancer (SMPC) is rare, and it is even less common to observe synchronous solid tumor with a hematological malignancy. We report five cases of solid tumor presented synchronously with hematological malignancy, all observed within a 2 year period at the oncology department of a university hospital in Shanghai, China. These individual cases included lung adenocarcinoma with chronic myelogenous leukemia, colon cancer with solitary plasmocytoma, gastric adenocarcinoma with diffuse large B cell non-Hodgkin's lymphoma, lung adenocarcinoma with multiple myeloma, and colon cancer with diffuse large B cell non-Hodgkin's lymphoma. It is challenging to therapeutically control the biological behavior of concurrent multiple primary tumors, and there is no standard treatment for such rare conditions. In this paper we discuss these five cases of SMPC and their treatments.

Keyword

Synchronous multiple primary neoplasms; Solid neoplasms; Hematologic neoplasms

MeSH Terms

Adenocarcinoma
China
Colonic Neoplasms
Hematologic Neoplasms
Incidence
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Lung
Lung Neoplasms
Lymphoma, Non-Hodgkin
Multiple Myeloma
Neoplasms, Multiple Primary
Plasmacytoma
Adenocarcinoma
Lung Neoplasms