Int J Thyroidol.  2016 May;9(1):43-46. 10.11106/ijt.2016.9.1.43.

Thyroid Hemiagenesis Associated with Papillary Thyroid Carcinoma

• Park I
• Choi JH
• Kim JH
• Kim JS

• KMID: 2164916
• DOI: http://doi.org/10.11106/ijt.2016.9.1.43

Abstract

Thyroid hemiagenesis is a rare congenital anomaly that is caused by a developmental defect of a thyroid. Previous reports indicate that thyroid cancer associated with hemiagenesis is extremely rare. A 47-year-old woman presented with single nodule in the right thyroid gland that was incidentally detected during a routine medical checkup. Ultrasonography showed a 1.5×1.2 cm sized ill-defined irregular hypoehoic nodule in the right thyroid and the isthmus was present. However, the left thyroid was not seen and thyroid was disconnected at left paraisthmic area. Fine-needle aspiration cytology confirmed that the right thyroid nodule was papillary thyroid carcinoma. Total thyroidectomy with bilateral central compartment node dissection was performed. Permanent pathologic finding was 1.3×1 cm sized classical type papillary thyroid carcinoma with nodular hyperplasia. There was extensive lymphatic invasion and 3 metastatic lymph nodes out of 4 in central compartment. In conclusion, although thyroid hemiagenesis associated with thyroid carcinoma is extremely rare, treatment strategy is not different with patients with normal anatomy. And the possibility of developing a thyroid carcinoma should be considered in patients with hemiagenesis. Furthermore, it requires awareness of anatomical difference around the thyroid gland during operation.

Keyword

Thyroid hemiagenesis; Thyroid cancer; Papillary thyroid carcinoma

MeSH Terms

Biopsy, Fine-Needle
Female
Humans
Hyperplasia
Lymph Nodes
Middle Aged
Thyroid Gland*
Thyroid Neoplasms*
Thyroid Nodule
Thyroidectomy
Ultrasonography

Figure

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  Fig. 1. Ultrasonography of the thyroid gland showing one hypoechoic nodule (arrow) in the right thyroid (A) and no thyroid tissue in the left thyroid (B).

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  Fig. 2. Operative finding of specimen showing absence of left lobe.

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