J Korean Neurol Assoc.  2016 May;34(2):133-137. 10.17340/jkna.2016.2.8.

Essential Cryoglobulinemia Presenting as Polyneuropathy and Cerebral Infarction

Affiliations
  • 1Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 2Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sonogung@gmail.com

Abstract

Cryoglobulinemia is a rare medical condition defined by presence of cryoglobulins in serum and it may cause hyperviscosity syndrome or systemic vasculitis in variable organs including the skin, joints, liver, kidneys, lungs and nervous system. A vasculitic polyneuropathy or mononeuritis multiplex commonly occurs. However, central nervous system complications of cryoglobulinemia including stroke, encephalopathy and seizures are rarely reported. We represent a case of essential cryoglobulinemic vasculitis manifested as a sensorimotor polyneuropathy combined with an acute ischemic stroke attack.

Keyword

Cryoglobulinemia; Polyneuropathy; Cerebral infarction

MeSH Terms

Central Nervous System
Cerebral Infarction*
Cryoglobulinemia*
Cryoglobulins
Joints
Kidney
Liver
Lung
Mononeuropathies
Nervous System
Polyneuropathies*
Seizures
Skin
Stroke
Systemic Vasculitis
Vasculitis
Cryoglobulins
Full Text Links
  • JKNA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2025 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr