Brain Neurorehabil.  2016 Mar;9(1):48-55. 10.12786/bn.2016.9.1.48.

Mirror Therapy Using Virtual Reality on the Wrsit of Rheumatoid Arthritis; Pilot Trial

Affiliations
  • 1Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Korea.
  • 2Department of Biomedical Engineering, University of Ulsan, Korea. kikoo@ulsan.ac.kr
  • 3Department of Physical Medicine and Rehabilitation, Ulsan University Hospital, University of Ulsan College of Medicine, Korea. chhwang1220ciba@yahoo.co.kr

Abstract


OBJECTIVE
Authors conducted the pilot trial to evaluate whether the virtual reality using mirror therapy induces analgesia and functional improvement to the patients of rheumatoid wrist arthritis. METHOD: Three patients with no symptom or sign of active phase at both wrists were recruited. Voluntary range of motion (ROM) of each wrist over as far as possible was recorded and then the same movement was recorded only over 60% of the previous one after break of 5 minutes. For the virtual reality treatment, the second recorded motion was reconstructed into the another one of as same ROM and spent time as the first one, providing confusing visual information to the patients while patients were instructed to reach only the red flags (60% ROM of 1st one). This exercise was repeated for 5 days. Numerous scales such as VAS, ROM, Michigan Hand Outcomes Questionaire (MHQ), Performance and Satisfaction in Activities of Daily Living (PS-ADL), patient-rated wrist evaluation (PRWE) were evaluated before and after repetition.
RESULTS
The increased satisfaction with their hands (satisfaction score of MHQ; 5.8 ± 2.3, [6-30]), improved ADL performances (PS-ADL score: 5.0 ± 3.5, [0-117]), and no side effect were noticed.
CONCLUSION
The virtual reality using mirror therapy may be safe and has some analgesic effect, which warrants a clinical trial in the future for the patients of rheumatoid wrist arthritis.

Keyword

analgesia; rheumatoid arthritis; virtual reality therapy; wrist

MeSH Terms

Activities of Daily Living
Analgesia
Arthritis
Arthritis, Rheumatoid*
Hand
Humans
Michigan
Range of Motion, Articular
Virtual Reality Exposure Therapy
Weights and Measures
Wrist

Figure

  • Fig. 1 Diagram of virtual reality. Patients were instructed to took a seat upright in a chair opposite to the table on which a monitor of virtual reality was placed, stretche their either of arm out into the support for the elbow, replace their wrist and hand in an anatomical neutral position under a camera to be seen fully in the center of the monitor, and their forearm and wrist were immobilized to the supports using Velcro strap.

  • Fig. 2 Preparation of virtual reality. Patients were instructed to grip a white poles using the palm surface so that the tip of the while pole was protruded beyond the ulnar border. Two red- colored round stickers of 1 cm in diameter were affixed to the center of wrist strap and the tip of the white pole respectively.

  • Fig. 3 Process of virtual reality. Patients were instructed to do flexion-extension wrist exercise again up- and down-ward to two red frags the location of which in a monitor was seen as the same as during the former exercise of full range. But virtual reality let the real-time movement of the wrist (white spot; 60% of previous range of motion) be seen to reach to the red flag in the pace of the same angular velocity.


Reference

1. Ramachandran VS, Rogers-Ramachandran D. Synaesthesia in phantom limbs induced with mirrors. Proc Biol Sci. 1996; 263:377–386.
Article
2. Ramachandran VS, Altschuler EL. The use of visual feedback, in particular mirror visual feedback, in restoring brain function. Brain. 2009; 132:1693–1710.
Article
3. Moseley GL. Using visual illusion to reduce at-level neuropathic pain in paraplegia. Pain. 2007; 130:294–298.
Article
4. Karmarkar A, Lieberman I. Mirror box therapy for complex regional pain syndrome. Anaesthesia. 2006; 61:412–413.
Article
5. Ramachandran VS, Seckel EL. Using mirror visual feedback and virtual reality to treat fibromyalgia. Med Hypotheses. 2010; 75:495–496.
Article
6. Yavuzer G, Selles R, Sezer N, Sutbeyaz S, Bussmann JB, Koseoglu F. Mirror therapy improves hand function in subacute stroke: a randomized controlled trial. Arch Phys Med Rehabil. 2008; 89:393–398.
Article
7. Lee HM, Li PC, Fan SC. Delayed mirror visual feedback presented using a novel mirror therapy system enhances cortical activation in healthy adults. J Neuroeng Rehabil. 2015; 12:56.
Article
8. Waljee JF, Chung KC, Kim HM, Burns PB, Burke FD, Wilgis EF. Validity and responsiveness of the Michigan Hand Questionnaire in patients with rheumatoid arthritis: a multicenter, international study. Arthritis Care Res (Hoboken). 2010; 62:1569–1577.
Article
9. Holmes NP, Crozier G, Spence C. When mirrors lie: visual capture of arm position impairs reaching performance. Cogn Affect Behav Neurosci. 2004; 4:193–200.
Article
10. Romano D, Bottini G, Maravita A. Perceptual effects of the mirror box training in normal subjects. Restor Neurol Neurosci. 2013; 31(4):373–386.
Article
11. Chung KC, Pillsbury MS, Walters MR, Hayward RA. Reliability and validity testing of the Michigan Hand Outcomes Questionnaire. J Hand Surg Am. 1998; 23:575–587.
Article
12. Archenholtz B, Dellhag B. Validity and reliability of the instrument Performance and Satisfaction in Activities of Daily Living (PS-ADL) and its clinical applicability to adults with rheumatoid arthritis. Scand J Occup Ther. 2008; 15:13–22.
Article
13. MacDermid JC, Turgeon T, Richards RS, Beadle M, Roth JH. Patient rating of wrist pain and disability: a reliable and valid measurement tool. J Orthop Trauma. 1998; 12:577–586.
Article
14. Norkin C WJ. Measurement of joint motion: a guide to goniometry. Philadelphia, PA: Davis Company;1995. p. 89–90.
15. Darnall BD, Li H. Home-based self-delivered mirror therapy for phantom pain: a pilot study. J Rehabil Med. 2012; 44:254–260.
Article
16. Botvinick M, Cohen J. Rubber hands feel touch that eyes see. Nature. 1998; 391:756.
Article
17. Garry MI, Loftus A, Summers JJ. Mirror, mirror on the wall: viewing a mirror reflection of unilateral hand movements facilitates ipsilateral M1 excitability. Exp Brain Res. 2005; 163:118–122.
Article
18. Harris AJ. Cortical origin of pathological pain. Lancet. 1999; 354:1464–1466.
Article
19. Flor H, Elbert T, Knecht S, Wienbruch C, Pantev C, Birbaumer N. Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature. 1995; 375:482–484.
Article
20. Flor H, Denke C, Schaefer M, Grusser S. Effect of sensory discrimination training on cortical reorganisation and phantom limb pain. Lancet. 2001; 357:1763–1764.
Article
21. Maihofner C, Handwerker HO, Neundorfer B, Birklein F. Cortical reorganization during recovery from complex regional pain syndrome. Neurology. 2004; 63:693–701.
Article
22. Pleger B, Tegenthoff M, Ragert P, Forster AF, Dinse HR, Schwenkreis P. Sensorimotor retuning [corrected] in complex regional pain syndrome parallels pain reduction. Ann Neurol. 2005; 57:425–429.
Article
23. Kolb B, Whishaw IQ. Brain plasticity and behavior. Annu Rev Psychol. 1998; 49:43–64.
Article
24. Funase K, Tabira T, Higashi T, Liang N, Kasai T. Increased corticospinal excitability during direct observation of self-movement and indirect observation with a mirror box. Neurosci Lett. 2007; 419:108–112.
Article
25. Touzalin-Chretien P, Ehrler S, Dufour A. Dominance of vision over proprioception on motor programming: evidence from ERP. Cereb Cortex. 2010; 20:2007–2016.
Article
26. Schaefer M, Flor H, Heinze HJ, Rotte M. Morphing the body: illusory feeling of an elongated arm affects somatosensory homunculus. Neuroimage. 2007; 36:700–705.
Article
27. Schaefer M, Heinze HJ, Rotte M. My third arm: shifts in topography of the somatosensory homunculus predict feeling of an artificial supernumerary arm. Hum Brain Mapp. 2009; 30:1413–1420.
Article
28. Egsgaard LL, Petrini L, Christoffersen G, Arendt-Nielsen L. Cortical responses to the mirror box illusion: a high-resolution EEG study. Exp Brain Res. 2011; 215:345–357.
Article
29. Liepert J, Miltner WH, Bauder H, Sommer M, Dettmers C, Taub E. Motor cortex plasticity during constraint-induced movement therapy in stroke patients. Neurosci Lett. 1998; 250:5–8.
Article
30. Kang YJ, Ku J, Han K, Kim SI, Yu TW, Lee JH. Development and clinical trial of virtual reality-based cognitive assessment in people with stroke: preliminary study. Cyberpsychol Behav. 2008; 11:329–339.
Article
31. Keshavarz B, Hecht H. Validating an efficient method to quantify motion sickness. Hum Factors. 2011; 53:415–426.
Article
Full Text Links
  • BN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr