J Vet Sci.  2015 Mar;16(1):121-126. 10.4142/jvs.2015.16.1.121.

Factors affecting the success of resynchronization protocols with or without progesterone supplementation in dairy cows

• Forro A
• Tsousis G
• Beindorff
• Sharifi AR
• Brozos C
• Bollwein H

• KMID: 2160829
• DOI: http://doi.org/10.4142/jvs.2015.16.1.121

Abstract

The objective of this study was to investigate factors that influence the success of resynchronization protocols for bovines with and without progesterone supplementation. Cow synchronized and not found pregnant were randomly assigned to two resynchronization protocols: ovsynch without progesterone (P4) supplementation (n = 66) or with exogenous P4 administered from Days 0 to 7 (n = 67). Progesterone levels were measured on Days 0 and 7 of these protocols as well as 4 and 5 days post-insemination. Progesterone supplementation raised the P4 levels on Day 7 (p < 0.05), but had no overall effect on resynchronization rates (RRs) or pregnancy per artificial insemination (P/AI). However, cows with Body Condition Score (BCS) > 3.5 had increased P/AI values while cows with BCS < 2.75 had decreased P/AI rates after P4 supplementation. Primiparous cows had higher P4 values on Day 7 than pluriparous animals (p = 0.04) and tended to have higher RRs (p = 0.06). Results of this study indicate that progesterone supplementation in resynchronization protocols has minimal effects on outcomes. Parity had an effect on the levels of circulating progesterone at initiation of the protocol, which in turn influenced the RR.

Keyword

ovsynch; progesterone; resynchronization

MeSH Terms

Animals
Cattle/*physiology
Dinoprost/administration & dosage/*pharmacology
Estrus Synchronization/*drug effects/methods
Female
Fertility Agents/administration & dosage/pharmacology
Gonadotropin-Releasing Hormone/administration & dosage/*pharmacology
Insemination, Artificial/veterinary
Ovulation/drug effects
Pregnancy
Progesterone/administration & dosage/*pharmacology
Tromethamine/administration & dosage/*pharmacology
Dinoprost
Fertility Agents
Gonadotropin-Releasing Hormone
Progesterone
Tromethamine

Figure

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  Fig. 1 Resynchronization protocols with or without P4 supplementation. GnRH: gonadotropin-releasing hormone, PGF2: prostaglandin F2α, TAI: timed artificial insemination, PRID: progesterone-releasing intravaginal device, p.i.: post insemination, B: blood samples, US: ultrasonography.

• 

  Fig. 2 Effect of P4 supplementation with a resynchronization protocol on different body condition score categories. P/AI: pregnancy per AI. *p < 0.05.

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