Ann Dermatol.  2003 Mar;15(1):12-14. 10.5021/ad.2003.15.1.14.

Solitary Malignant Gastrointestinal Stromal Tumor Associated with a Neurofibromatosis Type I

• Mo HJ
• Kim HO
• Kim CW
• Kim TY

• KMID: 2158671
• DOI: http://doi.org/10.5021/ad.2003.15.1.14

Abstract

From the Department of Dermatology, College of Medicine, The Catholic University of Korea, Kangnam St. Mary's Hospital, 505, Banpo-Dong, Seocho-Gu, 137-040, Seoul, Korea, Gastrointestinal stromal tumors are usually late manifestations of neurofibromatosis (von Recklinghausen's disease) and most become clinically apparent in middle-aged patients as multiple benign tumors. To our review of the literature, solitary malignant stromal tumor of gastrointestinal tract is exceptionally rare in von Recklinghausen's disease. We herein present a case of solitary jejunal stromal tumor in a 50-year-old woman with NF1, which histopathologically showed a malignant change and combined smooth muscle-neural type.

Keyword

Neurofibromatosis Type I; Gastrointestinal Stromal Tumor

MeSH Terms

Dermatology
Female
Gastrointestinal Stromal Tumors*
Gastrointestinal Tract
Humans
Korea
Middle Aged
Neurofibromatoses*
Neurofibromatosis 1*
Seoul