Yonsei Med J.  2013 Jul;54(4):942-948. 10.3349/ymj.2013.54.4.942.

Associations of Moderate to Severe Asthma with Obstructive Sleep Apnea

• Byun MK
• Park SC
• Chang YS
• Kim YS
• Kim SK
• Kim HJ
• Chang J
• Ahn CM
• Park MS

• KMID: 2158230
• DOI: http://doi.org/10.3349/ymj.2013.54.4.942

Abstract

PURPOSE
This study aimed to evaluate the correlation between associating factors of moderate to severe asthma with obstructive sleep apnea (OSA).
MATERIALS AND METHODS
One hundred and sixty-seven patients who visited the pulmonary and sleep clinic in Severance Hospital presenting with symptoms of sleep-disordered breathing were evaluated. All subjects were screened with ApneaLink. Thirty-two subjects with a high likelihood of having OSA were assessed with full polysomnography (PSG).
RESULTS
The mean age was 58.8+/-12.0 years and 58.7% of subjects were male. The mean ApneaLink apnea-hypopnea index (AHI) was 12.7+/-13.0/hr. The mean ApneaLink AHI for the 32 selected high risk patients of OSA was 22.3+/-13.2/hr, which was lower than the sleep laboratory-based PSG AHI of 39.1+/-20.5/hr. When OSA was defined at an ApneaLink AHI > or =5/hr, the positive correlating factors for OSA were age, male gender, and moderate to severe asthma.
CONCLUSION
Moderate to severe asthma showed strong correlation with OSA when defined at an ApneaLink AHI > or =5/hr.

Keyword

Apnea-hypopnea index; ApneaLink; asthma; obstructive sleep apnea; sleep-disordered breathing

MeSH Terms

Aged
Asthma/complications/epidemiology/*etiology
Comorbidity
Cross-Sectional Studies
Female
Humans
Male
Middle Aged
Polysomnography/instrumentation
Severity of Illness Index
Sleep Apnea Syndromes/epidemiology/etiology
Sleep Apnea, Obstructive/complications/epidemiology/*physiopathology

Figure

• 

  Fig. 1 Bland-Altman plot of ApneaLink apnea-hypopnea index (AHI) and polysomnography (PSG) AHI data.

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