J Korean Med Sci.  2013 Jan;28(1):16-24. 10.3346/jkms.2013.28.1.16.

Trends in the Incidence of Hospitalized Acute Myocardial Infarction and Stroke in Korea, 2006-2010

Affiliations
  • 1Department of Preventive Medicine, Dong-A University College of Medicine, Busan, Korea. yshong@dau.ac.kr
  • 2Regional Cardiocerebrovascular Disease Center, Dong-A University Hospital, Busan, Korea.
  • 3Korea Centers for Disease Control & Prevention, Cheongwon, Korea.
  • 4Department of Preventive Medicine, Kangwon National University Hospital, Regional Cardiocerebrovascular Disease Center, Chuncheon, Korea.
  • 5Department of Preventive Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
  • 6Regional Cardiocerebrovascular Disease Center, Kyungpook National University Hospital, Daegu, Korea.
  • 7Department of Health Policy and Management, Jeju National University School of Medicine, Jeju, Korea.
  • 8Department of Preventive Medicine, Jeju National University School of Medicine, Jeju, Korea.
  • 9Department of Preventive Medicine, Gyeongsang National University School of Medicine and Institute of Health Sciences, Jinju, Korea.
  • 10Regional Cardiocerebrovascular Disease Center, Gyeongsang National University Hospital, Jinju, Korea.
  • 11Department of Biomedical Science, Chonnam National University Medical School, Gwangju, Korea.
  • 12Department of Preventive Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.
  • 13Department of Preventive Medicine, Wonkwang University College of Medicine, Regional Cardiocerebrovascular Disease Center, Wonkwang University Hospital, Iksan, Korea.
  • 14Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea.
  • 15Regional Cardiocerebrovascular Disease Center, Chungnam National University Hospital, Daejeon, Korea.

Abstract

This study attempted to calculate and investigate the incidence of hospitalized acute myocardial infarction (AMI) and stroke in Korea. Using the National Health Insurance claim data, we investigated patients whose main diagnostic codes included AMI or stroke during 2006 to 2010. As a result, we found out that the number of AMI hospitalized patients had decreased since 2006 and amounted to 15,893 in 2010; and that the number of those with stroke had decreased since 2006 and amounted to 73,501 in 2010. The age-standardized incidence rate of hospitalized AMI, after adjustment for readmission, was 41.6 cases per 100,000-population in 2006, and had decreased to 29.4 cases in 2010 (for trend P < 0.001). In the case of stroke was estimated at 172.8 cases per 100,000-population in 2006, and had decreased to 135.1 cases in 2010 (for trend P < 0.001). In conclusion, the age-standardized incidence rates of both hospitalized AMI and stroke in Korea had decreased continuously during 2006 to 2010. We consider this decreasing trend due to the active use of pharmaceuticals, early vascular intervention, and the national cardio-cerebrovascular disease care project as the primary and secondary prevention efforts.

Keyword

Epidemiology; Acute Myocardial Infarction; Stroke; Patient Readmission

MeSH Terms

Acute Disease
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Child
Child, Preschool
Female
Hospitalization/*trends
Humans
Incidence
Infant
Infant, Newborn
Male
Middle Aged
Myocardial Infarction/*epidemiology
Patient Readmission
Republic of Korea/epidemiology
Sex Factors
Stroke/*epidemiology
Young Adult

Figure

  • Fig. 1 Age-standardized incidence rate of hospitalized AMI after adjustment for readmission, 2006-2010. (A) Incidence overall and by sex. (B) Incidence by age groups (year).

  • Fig. 2 Age-standardized incidence rate of stroke after adjustment for readmission, 2006-2010. (A) Incidence overall and by sex. (B) Incidence by age groups (year).


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Reference

1. Korea National Statistical Office. 2010 Annual report on the cause of death statistics. 2011. Daejeon, Korea: Korea National Statistical Office.
2. Korea Centers for Disease Control and Prevention. Development of strategy and action plans for major chronic diseases prevention and control. 2004. Seoul: Korea Centers for Disease and Prevention.
3. Hong JS, Kang HC, Lee SH, Kim J. Long-term trend in the incidence of AMI in Korea: 1997-2007. Korean Circ J. 2009. 39:467–476.
4. Tunstall-Pedoe H, Kuulasmaa K, Mähönen M, Tolonen H, Ruokokoski E, Amouyel P. Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA project populations. Monitoring trends and determinants in cardiovascular disease. Lancet. 1999. 353:1547–1557.
5. Feigin VL, Lawes CM, Bennett DA, Barker-Collo SL, Parag V. Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review. Lancet Neurol. 2009. 8:355–369.
6. Parikh NI, Gona P, Larson MG, Fox CS, Benjamin EJ, Murabito JM, O'Donnell CJ, Vasan RS, Levy D. Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study. Circulation. 2009. 119:1203–1210.
7. Rosamond WD, Chambless LE, Heiss G, Mosley TH, Coresh J, Whitsel E, Wagenknecht L, Ni H, Folsom AR. Twenty-two-year trends in incidence of myocardial infarction, coronary heart disease mortality, and case fatality in 4 US communities, 1987-2008. Circulation. 2012. 125:1848–1857.
8. Yeh RW, Sidney S, Chandra M, Sorel M, Selby JV, Go AS. Population trends in the incidence and outcomes of AMI. N Engl J Med. 2010. 362:2155–2165.
9. Smolina K, Wright FL, Rayner M, Goldacre MJ. Determinants of the decline in mortality from AMI in England between 2002 and 2010: linked national database study. BMJ. 2012. 344:d8059.
10. Schmidt M, Jacobsen JB, Lash TL, Bøtker HE, Sørensen HT. 25 year trends in first time hospitalisation for AMI, subsequent short and long term mortality, and the prognostic impact of sex and comorbidity: a Danish nationwide cohort study. BMJ. 2012. 344:e356.
11. Takii T, Yasuda S, Takahashi J, Ito K, Shiba N, Shirato K, Shimokawa H. MIYAGI-AMI Study Investigators. Trends in acute myocardial infarction incidence and mortality over 30 years in Japan: report from the MIYAGI-AMI Registry Study. Circ J. 2010. 74:93–100.
12. Carandang R, Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Kannel WB, Wolf PA. Trends in incidence, lifetime risk, severity, and 30-day mortality of stroke over the past 50 years. JAMA. 2006. 296:2939–2946.
13. Rothwell PM, Coull AJ, Giles MF, Howard SC, Silver LE, Bull LM, Gutnikov SA, Edwards P, Mant D, Sackley CM, et al. Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet. 2004. 363:1925–1933.
14. Lee S, Shafe AC, Cowie MR. UK stroke incidence, mortality and cardiovascular risk management 1999-2008: time-trend analysis from the General Practice Research Database. BMJ Open. 2011. 1:e000269.
15. Sivenius J, Tuomilehto J, Immonen-Räihä P, Kaarisalo M, Sarti C, Torppa J, Kuulasmaa K, Mähönen M, Lehtonen A, Salomaa V. FINSTROKE study. Continuous 15-year decrease in incidence and mortality of stroke in Finland: the FINSTROKE study. Stroke. 2004. 35:420–425.
16. Kubo M, Kiyohara Y, Kato I, Tanizaki Y, Arima H, Tanaka K, Nakamura H, Okubo K, Iida M. Trends in the incidence, mortality, and survival rate of cardiovascular disease in a Japanese community: the Hisayama study. Stroke. 2003. 34:2349–2354.
17. Chau PH, Woo J, Goggins WB, Tse YK, Chan KC, Lo SV, Ho SC. Trends in stroke incidence in Hong Kong differ by stroke subtype. Cerebrovasc Dis. 2011. 31:138–146.
18. National Health Insurance Corporation, Health Insurance Review & Assessment Service. 2010 National Health Insurance statistical yearbook. 2011. Seoul, Korea: National Health Insurance Corporation, Health Insurance Review & Assessment Service.
19. Korea National Statistical Office. Korean standard classification of diseases. 2010. Daejeon, Korea: Korea National Statistical Office.
20. Brameld KJ, Holman CD, Lawrence DM, Hobbs MS. Improved methods for estimating incidence from linked hospital morbidity data. Int J Epidemiol. 2003. 32:617–624.
21. Health Insurance Review & Assessment Service. 2011 Result of AMI evaluation. 2011. Seoul, Korea: Health Insurance Review & Assessment Service.
22. Rosamond WD, Chambless LE, Folsom AR, Cooper LS, Conwill DE, Clegg L, Wang CH, Heiss G. Trends in the incidence of myocardial infarction and in mortality due to coronary heart disease, 1987 to 1994. N Engl J Med. 1998. 339:861–867.
23. Roger VL, Weston SA, Gerber Y, Killian JM, Dunlay SM, Jaffe AS, Bell MR, Kors J, Yawn BP, Jacobsen SJ. Trends in incidence, severity, and outcome of hospitalized myocardial infarction. Circulation. 2010. 121:863–869.
24. Kleindorfer DO, Khoury J, Moomaw CJ, Alwell K, Woo D, Flaherty ML, Khatri P, Adeoye O, Ferioli S, Broderick JP, et al. Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke Study. Stroke. 2010. 41:1326–1331.
25. Heuschmann PU, Grieve AP, Toschke AM, Rudd AG, Wolfe CD. Ethnic group disparities in 10-year trends in stroke incidence and vascular risk factors: the South London Stroke Register (SLSR). Stroke. 2008. 39:2204–2210.
26. Abildstrom SZ, Rasmussen S, Rosén M, Madsen M. Trends in incidence and case fatality rates of AMI in Denmark and Sweden. Heart. 2003. 89:507–511.
27. World Health Organization. 2008-2013 Action plan for the global strategy for the prevention and control of noncommunicable diseases. 2008. accessed on 10 May 2012. Geneva: World Health Organization;Available at http://www.who.int/nmh/publications/9789241597418/en/index.html.
28. Ministry of Health, Welfare and Family Affairs. Guidebook of 2010 Major chronic disease management project. 2010. Seoul, Korea: Ministry of Health, Welfare and Family Affairs.
29. Scarborough P, Peto V, Bhatnagar P, Kaur A, Leal J, Luengo-Fernandez R, Gray A, Rayner M, Allender S. Stroke statistics 2009. 2011. accessed on 10 May 2012. Oxford, UK: British Heart Foundation;Available at http://www.bhf.org.uk/research/statistics/heart-statistics-publications.aspx.
30. Health Insurance Review & Assessment Service. Results of the first Coronary Artery Bypass Graft (CABG) evaluation. 2011. Seoul, Korea: Health Insurance Review & Assessment Service.
31. Park BJ, Sung JH, Park KD, Seo SW, Kim SW. Report of the evaluation for validity of discharged diagnosis in Korean Health Insurance database. 2003. Seoul, Korea: Seoul National University.
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