Ann Dermatol.  2012 Feb;24(1):112-114. 10.5021/ad.2012.24.1.112.

Numerous Mucin Nodules in a Patient with Seropositive Wide Spread Discoid Lupus Erythematosus

Affiliations
  • 1Department of Dermatology, Faculty of Medicine, Kagawa University, Kagawa, Japan. kyoneda@med.kagawa-u.ac.jp
  • 2Department of Dermatology, Jichi Medical University, Omiya Medical Center, Saitama, Japan.
  • 3Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Abstract

No abstract available.


MeSH Terms

Humans
Lupus Erythematosus, Discoid
Mucins
Mucins

Figure

  • Fig. 1 (A) Round, atrophic, erythematous, telangiectatic, and scaly plaques on the face. Irregular encroachments of the ear auricular cartilage and overlying skin were observed. (B, C) Multiple flesh-colored nodules were observed on the back (arrows). (D) Each nodule was slightly elevated.

  • Fig. 2 Histological findings. (A) Focal epidermal atrophy and hydropic degeneration in the basal layer were observed. Papillary edema and a mild perivascular mononuclear cell infiltrate were present in the dermis. The epidermal appendages were normal. Heavy mononuclear cell infiltrate of epidermal appendages was observed (H&E, ×4). (B) Alcian blue staining at pH 4 confirmed the acidic mucopolysaccharide nature of the amorphous material in the dermis. Scale bar: 500µm (Alcian Blue, ×4).


Reference

1. Sonntag M, Lehmann P, Megahed M, Ruzicka T, Kuhn A. Papulonodular mucinosis associated with subacute cutaneous lupus erythematosus. Dermatology. 2003. 206:326–329.
Article
2. Ortiz VG, Krishnan RS, Chen LL, Hsu S. Papulonodular mucinosis in systemic lupus erythematosus. Dermatol Online J. 2004. 10:16.
Article
3. Hazan C. Papulonodular mucinosis with subacute cutaneous lupus erythematosus. Dermatol Online J. 2004. 10:6.
Article
4. Bachmeyer C, Chesneau AM, Loirat C, Asensi D, Babinet JM, Blum L. Papulonodular mucinosis in a child with systemic lupus erythematosus. Pediatr Dermatol. 2007. 24:585–586.
Article
5. Shekari AM, Ghiasi M, Ghasemi E, Kani ZA. Papulonodular mucinosis indicating systemic lupus erythematosus. Clin Exp Dermatol. 2009. 34:e558–e560.
Article
6. McFadden N, Ree K, Søyland E, Larsen TE. Scleredema adultorum associated with a monoclonal gammopathy and generalized hyperpigmentation. Arch Dermatol. 1987. 123:629–632.
Article
Full Text Links
  • AD
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr