Ann Dermatol.  2012 Feb;24(1):11-15. 10.5021/ad.2012.24.1.11.

Analysis of Cardiovascular Risk Factors and Metabolic Syndrome in Korean Patients with Psoriasis

• Kim GW
• Park HJ
• Kim HS
• Kim SH
• Ko HC
• Kim BS
• Kim MB
• Sim EK

• KMID: 2156849
• DOI: http://doi.org/10.5021/ad.2012.24.1.11

Abstract

BACKGROUND
In previous studies, psoriasis has been reported to be associated with metabolic syndrome.
OBJECTIVE
The purpose of this study was to evaluate risk factors for metabolic syndrome in psoriasis patients and to compare the prevalence of metabolic syndrome in psoriasis and control groups.
METHODS
All patients (n=490) and controls (n=682) were investigated for cardiovascular risk factors, including central obesity, hypertension, fasting plasma glucose levels, and blood levels of triglycerides and high-density lipoprotein (HDL).
RESULTS
We found no statistical association between psoriasis and the prevalence of metabolic syndrome when controlling for age and gender. Among individual components of metabolic syndrome, only increased triglyceride levels was significantly prevalent in patients psoriasis. The incidence of other factors such as central obesity, hypertension, fasting plasma glucose and HDL in the psoriasis group were similar to or lower than those in the control group. Although psoriasis patients with metabolic syndrome had severe and large plaque-type psoriasis, the association of metabolic syndrome with the severity or clinical subtype of psoriasis was not significant after adjusting for age and gender.
CONCLUSION
Our results suggest that there is no close correlation between psoriasis and metabolic syndrome in Korean patients.

Keyword

Cardiovascular risk; Metabolic syndrome; Psoriasis

MeSH Terms

Fasting
Glucose
Humans
Hypertension
Incidence
Lipoproteins
Obesity, Abdominal
Plasma
Prevalence
Psoriasis
Risk Factors
Triglycerides
Glucose
Lipoproteins
Triglycerides

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