Ann Dermatol.  2011 Sep;23(Suppl 1):S116-S118. 10.5021/ad.2011.23.S1.S116.

A Case of a Subepidermal Calcified Nodule on the Sole without Trauma

  • 1Department of Dermatology, College of Medicine, Hallym University, Seoul, Korea.
  • 2Department of Pathology, College of Medicine, Hallym University, Seoul, Korea.


Subepidermal calcified nodule is an uncommon form of calcinosis cutis, which most commonly occurs in children. It usually presents as an asymptomatic, solitary verrucous nodule on the head and neck region, but occasionally as multiple lesions. Serum calcium and phosphorus levels are usually normal. Histopathology shows well-formed homogeneous eosinophilic material and granules in the upper dermis. Material in the dermis stained with von Kossa was positive. We report on an unusual case of a subepidermal calcified nodule occurring on the sole. A 21-month-old male presented with an oval-shaped, whitish, hard nodule measuring 5x5 mm on the left sole, without any previous history of trauma.


Calcified; Sole; Subepidermal

MeSH Terms



  • Fig. 1 An oval-shaped, whitish papule measuring 0.5×0.5 cm on an erythematous base of the left sole.

  • Fig. 2 Haematoxylin and eosin-stained sections showed a hyperkeratotic and acanthotic epidermis overlying a cystic structure in the upper dermis. The cystic space contained amorphous eosinophilic materials as multilobulated masses (H&E stain, ×40).

  • Fig. 3 Amorphous black to dark brown colored materials were confirmed as calcium by staining with von Kossa (von Kossa stain, ×40).


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