Ann Dermatol.  2011 Sep;23(Suppl 1):S88-S90. 10.5021/ad.2011.23.S1.S88.

A Case of Acrodermatitis Enteropathica Localized on the Hands and Feet with a Normal Serum Zinc Level

• Lee SY
• Jung YJ
• Oh TH
• Choi EH

• KMID: 2156760
• DOI: http://doi.org/10.5021/ad.2011.23.S1.S88

Abstract

Acrodermatitis enteropathica is classified as a congenital autosomal recessive type and an acquired transient type. This disease manifests as acral and periorificial dermatitis, alopecia, intractable diarrhea, and failure to thrive. Whereas the autosomal hereditary type is caused by malabsorption of zinc in the intestine, the acquired type is caused by low nutritional support or decreased peripheral release of zinc from blood. We experienced a case of a 5-month old, breast feeding, full-term female presenting with only acral bullous dermatitis without diarrhea, periorificial dermatitis and an abnormal serum zinc level.

Keyword

Acrodermatitis enteropathica; Palmoplantar; Zinc

MeSH Terms

Acrodermatitis
Alopecia
Breast Feeding
Dermatitis
Diarrhea
Failure to Thrive
Female
Foot
Hand
Humans
Intestines
Nutritional Support
Zinc
Acrodermatitis
Zinc

Figure

• 

  Fig. 1 Multiple tense bullae and vesicles on the distal parts of foot and hand.

• 

  Fig. 2 (A) Acute spongiotic dermatitis and infiltration of upper dermal inflammatory cells (H&E, ×40). (B) Cytoplasmic pallor, the arrow, intraepidermal vesicle formation in the upper epidermis (H&E, ×200).

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