Ann Dermatol.  2008 Dec;20(4):237-239. 10.5021/ad.2008.20.4.237.

Development of Halo Nevus Around Nevus Spilus as a Central Nevus, and the Concurrent Vitiligo

  • 1Department of Dermatology, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.


Halo nevus is a benign melanocytic nevus that is surrounded by a hypopigmented zone. The most frequent association with halo nevus is vitiligo, and this also appears in nearby regions, as well as at other remote sites. Although the mechanism for developing the depigmentation around nevus spilus is uncertain an immunologic process may be responsible for the finding of inflammatory infiltrates of the upper dermis in the depigmented lesions. We report here on a 13-year-old boy who showed a depigmented zone around a nevus spilus on the right side of his neck with simultaneous vitiligo lesions on the face.


Halo nevus; Nevus spilus; Vitiligo

MeSH Terms

Nevus, Halo
Nevus, Pigmented


  • Fig. 1 (A) A well demarcated, pale brown colored patch with multiple, scattered, dark brown speckles on the right side of the neck with a hypopigmented zone around the nevus. (B) In addition, lesions of vitiligo were found in the perioral, perinasal and periorbital regions.

  • Fig. 2 (A) The histopathology of the pale brown colored patch lesion revealed elongation of the rete ridges and increased melanin pigmentation in the basal layer of the epidermis. (B) Biopsy from the dark brown colored speckles showed increased melanin in the dermoepidermal junction and upper dermis. Mononuclear cells and lymphohistiocytes were infiltrated into the upper part of the dermis in both lesions (A, B) (S-100, ×100).


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