Ann Dermatol.  2007 Mar;19(1):19-21. 10.5021/ad.2007.19.1.19.

Invasive Squamous Cell Carcinoma of the Oral Mucosa Associated with HPV Type 53

Affiliations
  • 1Department of Dermatology, National Medical Center, Seoul, Republic of Korea. nmcderma@hanmail.net
  • 2Center for AIDS Research, National Institute of Health, Korea Center for Disease Control and Prevention, Seoul, Korea.

Abstract

A 77-year old man presented with a fungating mass on the oral mucosa and lip, which had an irregular margin. An incisional biopsy of the mass revealed an invasive squamous cell carcinoma. PCR analysis detected HPV DNA in the biopsy specimen. The HPV type was determined as HPV-53 by direct cycle sequencing. This is the first report of HPV-53 in an oral malignant tumor.

Keyword

HPV-associated cancer; HPV type 53; Invasive squamous cell carcinoma; Oral cancer; Oral squamous cell carcinoma

MeSH Terms

Aged
Biopsy
Carcinoma, Squamous Cell*
DNA
Humans
Lip
Mouth Mucosa*
Mouth Neoplasms
Polymerase Chain Reaction
DNA
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