Ann Occup Environ Med.  2014 ;26(1):50-50. 10.1186/s40557-014-0050-z.

Serum prostate-specific antigen levels and type of work in tire manufacturing workers

• Kim SH
• Jang KH
• Park WJ
• Kwon DH
• Kang WY
• Lim HM
• Moon JD

• KMID: 2153929
• DOI: http://doi.org/10.1186/s40557-014-0050-z

Abstract

OBJECTIVES
This study measures serum prostate-specific antigen (PSA) levels in tire-manufacturing workers, and attempts to find occupational or non-occupational factors that related to their PSA levels.
METHODS
A total of 1,958 healthy male workers (1,699 were production workers and 259 were office workers) took PSA measurement for analysis.
RESULTS
After adjusting for age, body mass index, hypertension, regular exercise, alcohol drinking and smoking, which were significantly related to serum PSA levels or known related factors of serum PSA levels, the geometric mean PSA levels were significantly high in the office workers (p = 0.017), the older age group (p < 0.001), the group with hypertension (p = 0.046) and the group of individuals that do not exercise regularly (p = 0.015) and the office workers were more likely to have a serum PSA level of > or =4.0 (OR 7.73, 95% CI: 2.78-21.46) or 2.5 ng/mL (OR 2.74, 95% CI: 1.49-5.08). After stratifying by age and adjusting aforementioned covariates, office workers 50 years of age and older had the significantly higher geometric mean PSA levels (p = 0.017) and were more likely to have a serum PSA level of > or =4.0 ng/mL (OR 12.90, 95% CI: 3.65-45.64) or 2.5 ng/mL (OR 3.90, 95% CI: 1.64-9.25) than production workers 50 years of age and older.
CONCLUSIONS
This study showed that serum PSA levels were significantly higher among the group with hypertension or the group of individuals that did not exercise regularly or group of office workers who were considered to have lesser physical activities.

Keyword

Occupations; Physical activity; Prostate-specific antigen; Sedentary lifestyle

MeSH Terms

Alcohol Drinking
Body Mass Index
Humans
Hypertension
Male
Motor Activity
Occupations
Prostate-Specific Antigen*
Sedentary Lifestyle
Smoke
Smoking
Prostate-Specific Antigen
Smoke