Ann Occup Environ Med.  2014 ;26(1):42-42. 10.1186/s40557-014-0042-z.

The association between shift work and hyperuricemia in steelmaking male workers

• Oh JS
• Choi WJ
• Lee MK
• Han SW
• Song SH
• Yun JW
• Han SH

• KMID: 2153924
• DOI: http://doi.org/10.1186/s40557-014-0042-z

Abstract

OBJECTIVES
The aim of this study was to examine the association between shift work and hyperuricemia among steel company workers.
METHODS
We examined 1,029 male workers at a Korean steel company between June 6 and June 28, 2013. We conducted anthropometric measurements, questionnaire surveys, and blood tests. Hyperuricemia was defined as a serum uric acid concentration of > or =7.0 mg/dL. Logistic regression analyses were performed. In the full model, analysis was adjusted for covariates including age, body mass index, lifestyle factors, and comorbidities. The odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated for all models.
RESULTS
The participants included 276 daytime workers and 753 shift workers. Among daytime workers, 72 (26.1%) individuals had hyperuricemia, as did 282 (37.5%) individuals among shift workers (p <0.001). There was a statistically significant association between shift work and hyperuricemia. In the unadjusted model, the OR of shift work was 1.70 (95% CI 1.25-2.31) for hyperuricemia. In the full model, the OR of shift work was also statistically significant after adjustment for covariates (OR 1.41, 95% CI 1.02-1.96).
CONCLUSIONS
Among male steel workers, a significant association between shift work and hyperuricemia was observed.

Keyword

Hyperuricemia; Shift work; Job schedule

MeSH Terms

Body Mass Index
Comorbidity
Hematologic Tests
Humans
Hyperuricemia*
Life Style
Logistic Models
Male*
Odds Ratio
Steel
Uric Acid
Steel
Uric Acid