J Pathol Transl Med.  2015 Jul;49(4):339-342. 10.4132/jptm.2015.04.28.

Ureteral Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue, Chronic Inflammation, and Renal Artery Atherosclerosis

Affiliations
  • 1Department of Pathology, Eulji General Hospital, Eulji University College of Medicine, Seoul, Korea.
  • 2Department of Radiology, Eulji General Hospital, Eulji University College of Medicine, Seoul, Korea.
  • 3Department of Internal Medicine, Eulji General Hospital, Eulji University College of Medicine, Seoul, Korea.
  • 4Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. jrhuh@amc.seoul.kr

Abstract

No abstract available.


MeSH Terms

Atherosclerosis*
Inflammation*
Lymphoma, B-Cell, Marginal Zone*
Renal Artery*
Ureter*

Figure

  • Fig. 1. (A) Contrast-enhanced axial computed tomography scan of the abdomen shows thickening with enhancement of the right renal pelvis wall with perinephric soft tissue infiltration (arrows) and hydroureteronephrosis. (B) Positron emission tomography computed tomography reveals hypermetabolic lesions in multiple neck, axillary, mediastinal, and pelvic lymph nodes as well as the chest, abdominal wall, left parotid gland, and right thigh.

  • Fig. 2. Grossly, the specimen shows whitish yellow solid lesions along the renal pelvis and the ureter (black arrow), forming a concentric mass (black arrow, lower inset) compressing the ureter lumen. Renal artery surrounded by white solid lesions (black arrow, upper inset) shows atheromatous plaques and a thrombus (white arrow, upper inset).

  • Fig. 3. Microscopic features of mucosa-associated lymphoid tissue lymphoma and adjacent chronic inflammation. (A) Tumor cells infiltrating the perimuscular layer of the ureter form lymphoid follicles with follicular colonization. Immunohistochemically, tumor cells are diffusely positive for CD20 (B) and accompanying T cells are mostly CD4 positive (C). (D) Peripelvic adipose tissue shows a mixed infiltrate of lymphoplasma cells, eosinophils, and histiocytes with fibroblastic proliferation.


Reference

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