J Korean Geriatr Soc.  2015 Dec;19(4):244-247. 10.4235/jkgs.2015.19.4.244.

Regression of a Mucosa-Associated Lymphoid Tissue Lymphoma of the Urinary Bladder After Helicobacter pylori Eradication Therapy in an Elderly Patient

• Park JH
• Kim NY
• Lee JA
• Rim CB
• Song YW
• Kim Y
• Kim S
• Kim JW
• Shin SH
• Gong S

• KMID: 2150948
• DOI: http://doi.org/10.4235/jkgs.2015.19.4.244

Abstract

Primary low-grade lymphoma of the mucosa-associated lymphoid tissue (MALT) type lymphoma of the bladder is rare. A relationship between MALT lymphoma of the urinary bladder and chronic cystitis has been proposed by some reports. Additionally a relationship between MALT lymphoma of the urinary bladder and Helicobacter pylori has been reported. Here we present a case of regression of urinary bladder MALT lymphoma after antibiotic therapy, using H. pylori eradication protocol in an elderly patient, who had a high risk of treatment related mortality in curative systemic chemotherapy. The patient is a 74-year-old woman who had a history of chronic cystitis. She was diagnosed with stage IIA primary MALT lymphoma of the urinary bladder and was treated with H. pylori eradication triple therapy for 2 weeks. After 2 months, there was a marked regression of the bladder MALT lymphoma lesion in a computed tomography scan of the abdomen.

Keyword

MALT lymphoma; Urinary bladder; Helicobacter pylori; Chronic cystitis

MeSH Terms

Abdomen
Aged*
Cystitis
Drug Therapy
Female
Helicobacter pylori*
Helicobacter*
Humans
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell, Marginal Zone*
Lymphoma, Non-Hodgkin
Mortality
Urinary Bladder*