Korean J Helicobacter Up Gastrointest Res.  2015 Dec;15(4):270-273. 10.7704/kjhugr.2015.15.4.270.

A Case of Gastric Langerhans Cell Histiocytosis with Spontaneous Regression

• Hwang KB
• Ham JS
• Hwang S
• Jung SH
• Lee JH

• KMID: 2149710
• DOI: http://doi.org/10.7704/kjhugr.2015.15.4.270

Abstract

A 44-year-old male was followed-up with esophagogastroduodenoscopy due to an esophageal submucosal tumor. On the lesser curvature of the gastric low body, a 0.5 cm sized round elevated lesion with hyperemia was noticed. Two pieces of biopsy were taken from this lesion for histopathologic examination. Histology showed Langerhans cell infiltration. Immunohistochemical staining was positive for CD1a antigen, which confirmed the diagnosis of Langerhans cell histiocytosis. There was no evidence of other organ involvement. The lesions spontaneously disappeared 4 months later without any treatment. We report a very rare case of gastric Langerhans cell histiocytosis.

Keyword

Langerhans cell histiocytosis; Neoplasm regression, spontaneous; Stomach; CD1a antigen

MeSH Terms

Adult
Biopsy
Diagnosis
Endoscopy, Digestive System
Histiocytosis, Langerhans-Cell*
Humans
Hyperemia
Male
Neoplasm Regression, Spontaneous
Stomach