J Korean Ophthalmol Soc.  1998 Jul;39(7):1340-1344.

The Difference in Graft Rejection between Two Corneal Preservation Methods(Moist Chamber vs Optisol)

• Lee ET
• Myung YW
• Shin JA

Abstract

To know the difference in graft rejection after corneal transplantation between moist chamber and Optisol(Chiron Co. Irvine, CA, U.S.A.) as cornea preservation methods, we compared two groups involving 50 patients(71 eyes) who had undergone partially penetrating keratoplasty (PPKP) for the treatment of keratoconus or corneal dystrophy from 1991 to 1995. The graft rejection had occurred in 10 of 40 eyes(25%) in moist chamber group and 9 of 31 eyes(29%) in Optisol group, and the cases of permanent corneal opacity after rejection were 5 of 40 eyes(12.5%), 3 of 31 eyes(9.7%) respectively. No difference in the two groups was statistically significant(P<0.05). We found the fact that the difference did not exist in the results from graft rejection after PPKP using moist chamber method for short preservation period, or Optisol method for the relatively long period allowing serological and immunological screen test.

Keyword

Moist chamber; Optisol; Partially penetrating keratoplasty(PPKP); Graft rejection

MeSH Terms

Cornea
Corneal Opacity
Corneal Transplantation
Graft Rejection*
Keratoconus
Keratoplasty, Penetrating
Transplants*