Korean J Dermatol.  2000 Dec;38(12):1696-1698.

A Case of Early-Onset Childhood Sarcoidosis

• Whang SW
• Kim DS
• Lee KH

Abstract

Early-onset childhood sarcoidosis is a unique form of the disease characterized by the triad of rash, uveitis, and arthritis in patients presenting before age 4 years. We report a case of early onset childhood sarcoidosis in a 4-year-old girl. She presented with fever, right ankle joint swelling, multiple skin lesions on whole body and was diagnosed as juvenile rheumatoid arthritis in padiatric department. She was transferred to dermatologic department for skin evaluation, histological investigation revealed well-circumscribed, non-caseating naked granuloma with epitheloid cells, histiocytes, lymphocytes on the upper dermis. Laboratory evaluation, chest X-ray, and ophthalmologic evaluation are all within normal limit. She is treated with systemic steroid, methotrexate, non-steroidal anti-inflammatory drugs and follow up evaluation will be planned for possible eye involvement.

Keyword

Childhood; Sarcoidosis

MeSH Terms

Ankle Joint
Arthritis
Arthritis, Juvenile
Child, Preschool
Dermis
Exanthema
Female
Fever
Granuloma
Histiocytes
Humans
Lymphocytes
Methotrexate
Sarcoidosis*
Skin
Thorax
Uveitis
Methotrexate