Korean J Dermatol.  2011 Jan;49(1):86-89.

Neutrophilic Dermatosis of the Dorsal Hands

• Choi SR
• Kim WJ
• Lee HJ
• Kim DH
• Yoon MS

Abstract

Neutrophilic dermatosis of the dorsal hands (NDDH) is a rare, localized variant of Sweet syndrome, and it was first described by Galaria et al. in 2000. It usually occurs in middle-aged women and it is characterized by erythematous papules, plaques, pustules and hemorrhagic bullae that are generally located on the dorsal hands. The histopathological findings show prominent papillary dermal edema and a dense dermal neutrophilic infiltration. A neutrophilic infiltrate can also cause a variable degree of vascular damage: endothelial cell swelling, RBC extravasation, leukocytoclasia and fibrin deposition within the walls of vessels. We report here on a case of NDDH in a 50-year-old man who was treated with oral corticosteroid and the NDDH recurred after 9 months.

Keyword

Dorsal hand; Neutrophilic dermatosis; Sweet syndrome

MeSH Terms

Blister
Edema
Endothelial Cells
Female
Fibrin
Hand
Humans
Middle Aged
Neutrophils
Skin Diseases
Sweet Syndrome
Fibrin